Evidence supporting the use of: Vitamin B12 (mixed)
For the health condition: Pregnancy (herbs and supplements for)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B12 is scientifically validated as an important nutrient during pregnancy. Adequate B12 intake is crucial for proper fetal growth and neurological development, as well as for maternal health. B12 is required for DNA synthesis, red blood cell formation, and neurological function. Deficiency during pregnancy can lead to megaloblastic anemia in the mother and increased risk of neural tube defects, developmental delays, and failure to thrive in the infant. Several clinical studies and reviews have demonstrated that low maternal B12 status is associated with negative pregnancy outcomes, including preterm birth and low birth weight. Supplementation is particularly important for women with dietary restrictions (e.g., vegetarians, vegans) or malabsorption syndromes, as B12 is primarily found in animal-derived foods. Leading medical organizations, such as the American College of Obstetricians and Gynecologists and the World Health Organization, recommend B12 supplementation for pregnant women at risk of deficiency. However, B12 is not typically used as a treatment for pregnancy itself, but rather to prevent or address deficiency and related complications during pregnancy. Overall, the role of B12 in supporting healthy pregnancies is well-established and based on strong scientific evidence.

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