Evidence supporting the use of: Vitamin B6 (Pyridoxine HCl)
For the health condition: Pregnancy (herbs and supplements for)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B6 (Pyridoxine HCl) is scientifically validated as a treatment for certain pregnancy-related conditions, most notably for the management of nausea and vomiting during pregnancy (NVP), often referred to as "morning sickness." Multiple randomized controlled trials and systematic reviews have demonstrated that vitamin B6 supplementation can significantly reduce the severity of nausea and vomiting in pregnant women compared to placebo. The American College of Obstetricians and Gynecologists (ACOG) recommends vitamin B6 as a first-line therapy for mild to moderate NVP, either alone or in combination with doxylamine. Typical dosages studied range from 10 to 25 mg three times daily.

Vitamin B6 is generally considered safe in pregnancy when used at recommended doses, with adverse effects being rare at these levels. Its mechanism is thought to involve its role as a coenzyme in neurotransmitter synthesis, potentially reducing the stimuli that trigger nausea. While vitamin B6 is not used to support general pregnancy health or prevent complications such as preeclampsia, its targeted use for NVP is well-supported by current clinical guidelines and research evidence. Therefore, its use in pregnancy is justified by scientific evidence specifically for nausea and vomiting, with a strong evidence rating of 4 out of 5.

More about Vitamin B6 (Pyridoxine HCl)
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