Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Vitex agnus-castus, commonly known as chaste tree berry, has a long history of traditional use for supporting women’s reproductive health, specifically in addressing menstrual irregularities and symptoms of premenstrual syndrome (PMS). It is believed to influence hormone balance, particularly by supporting progesterone production indirectly through modulation of the pituitary gland and prolactin secretion. Historical records from ancient Greece and Rome document its use for menstrual disorders and as a remedy for female hormonal imbalances.

Scientific studies investigating Vitex’s efficacy are moderate in quality and number. Some randomized controlled trials suggest it may reduce PMS symptoms, possibly via effects on pituitary hormones rather than direct progesterone elevation. The exact mechanism remains unclear, and current evidence does not robustly confirm a direct increase in progesterone levels. However, Vitex appears to exert a dopaminergic effect, lowering prolactin, which can secondarily favor progesterone production in some women with specific hormonal imbalances.

Overall, while traditional use of Vitex agnus-castus for supporting the progesterone system is well established, scientific validation is less definitive but does provide some support for its role in improving menstrual health and hormonal balance. More rigorous, large-scale clinical trials are needed to clarify its specific effects on progesterone and related reproductive hormones.

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