Relationship: Prostaglandins and DHA (docosahexaeonic acid)

Evidence supporting the use of: DHA (docosahexaeonic acid)
For the body system: Prostaglandins

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

DHA (docosahexaenoic acid) is an omega-3 polyunsaturated fatty acid that plays an important role in modulating inflammatory processes in the body, including those mediated by prostaglandins. Prostaglandins are lipid compounds that have diverse hormone-like effects, notably in inflammation and immune responses. DHA is incorporated into cell membranes and serves as a substrate for the production of bioactive lipid mediators, such as resolvins and protectins, which can influence the synthesis and activity of prostaglandins and other eicosanoids.

Several scientific studies have shown that omega-3 fatty acids, including DHA, can shift the balance of eicosanoid production toward less inflammatory prostaglandins (such as PGE3) and away from more pro-inflammatory forms (such as PGE2) produced from arachidonic acid (an omega-6 fatty acid). This shift is believed to be one of the mechanisms by which DHA and other omega-3s exert their anti-inflammatory effects.

While there is evidence from clinical and mechanistic studies supporting the role of DHA in modulating prostaglandin synthesis and function, most research has focused on broader inflammatory outcomes or specific conditions (e.g., cardiovascular disease, rheumatoid arthritis) rather than directly on the "prostaglandin body system" as a standalone concept. Thus, the evidence is moderate (rating of 3), with support for a modulatory effect but not always directly tied to clinical endpoints related solely to prostaglandins.

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Other body systems supported by DHA (docosahexaeonic acid)

Arteries
Blood
Brain
Circulatory System
Eyes
Heart
Immune System
Nerves
Parasympathetic Nervous System
Prostaglandins
Reproductive System
Skin

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Evidence supporting the use of: DHA (docosahexaeonic acid)
For the body system: Prostaglandins

Table of Contents

Synopsis

Other ingredients that support Prostaglandins

Other body systems supported by DHA (docosahexaeonic acid)

Products containing DHA (docosahexaeonic acid)

Health Concerns

Brands

Evidence supporting the use of: DHA (docosahexaeonic acid)For the body system: Prostaglandins

Table of Contents

Synopsis

Other ingredients that support Prostaglandins

Other body systems supported by DHA (docosahexaeonic acid)

Products containing DHA (docosahexaeonic acid)

Evidence supporting the use of: DHA (docosahexaeonic acid)
For the body system: Prostaglandins