Evidence supporting the use of: Anti-aromatase
For the body system: Prostate

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Anti-aromatase agents are substances that inhibit the enzyme aromatase, which is responsible for converting androgens (such as testosterone) into estrogens. The rationale for their use in supporting prostate health, particularly in the context of prostate cancer or benign prostatic hyperplasia (BPH), stems from the role of estrogens and estrogens' metabolites in prostate tissue. Scientific studies have shown that high levels of estrogen, or an imbalance between estrogen and androgen, may contribute to the development and progression of prostate diseases.

Several aromatase inhibitors (such as anastrozole, letrozole, and exemestane) are well-studied in the context of breast cancer but have also been investigated for prostate health. Preclinical studies and some early-phase clinical trials suggest that reducing estrogen production via aromatase inhibition can modulate prostate tissue growth and may be beneficial in managing certain prostate conditions. However, the evidence is not yet robust, with limited large-scale, long-term clinical trials in men with prostate disease. The use of anti-aromatase agents for prostate health is sometimes considered in cases of hormone-sensitive prostate cancer, often as part of experimental or adjunctive protocols rather than standard care.

In summary, while there is a biologically plausible mechanism and some scientific evidence supporting the use of anti-aromatase agents in prostate health, the clinical evidence is moderate and not yet definitive. Use should be guided by a healthcare professional, considering the potential side effects and the need for more extensive research.

More about anti-aromatase
More about Prostate

Other body systems supported by anti-aromatase

Estrogen
Male Reproductive System
Prostate
Testes
Testosterone

Products containing anti-aromatase

We currently have no products on Vitabase that contain this ingredient.