Evidence supporting the use of: Beta Sitosterol
For the body system: Prostate

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Beta-sitosterol is a plant-derived sterol commonly used to support prostate health, particularly in relation to benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland. Scientific evidence supporting its use comes from several randomized, placebo-controlled clinical trials and meta-analyses. A notable meta-analysis published in the journal British Journal of Urology (1999) reviewed data from four randomized, double-blind, placebo-controlled trials involving a total of 519 men with BPH. The results indicated that beta-sitosterol significantly improved urinary symptom scores and flow measures compared to placebo, though it did not reduce prostate size.

Despite these benefits, the duration of the studies was limited (generally less than 6 months), and long-term safety and efficacy data are lacking. Furthermore, beta-sitosterol is not a substitute for medical treatment in cases of severe urinary obstruction or prostate cancer. Major clinical guidelines do not universally recommend beta-sitosterol, but acknowledge its modest effectiveness for symptom management. Overall, the evidence base suggests moderate scientific support for beta-sitosterol in managing symptoms related to BPH, but more large-scale, long-term research is needed to further clarify its role and optimal use.

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