Evidence supporting the use of: Cucurbita
For the body system: Prostate

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cucurbita, commonly known as pumpkin, particularly the seeds (Cucurbita pepo), has been traditionally used and increasingly studied for its potential benefits in supporting prostate health, especially in the context of benign prostatic hyperplasia (BPH). There is scientific validation for its use, though the evidence is moderate rather than strong.

Several clinical studies and reviews have examined pumpkin seed extract's effects on lower urinary tract symptoms (LUTS) associated with BPH. The seeds are rich in phytosterols, essential fatty acids, and other compounds believed to exert anti-inflammatory and possible anti-androgenic effects. A 2014 randomized, double-blind, placebo-controlled trial published in Urologia Internationalis found that pumpkin seed oil improved International Prostate Symptom Scores (IPSS) in men with BPH over 12 months, compared to placebo. Other studies have reported mild to moderate improvements in urinary flow and symptom scores with pumpkin seed or its oil.

Systematic reviews generally conclude that while the effect size is modest, pumpkin seed extract is safe and may be beneficial as a complementary approach to prostate health, especially for mild to moderate symptoms. The precise mechanisms are not fully understood, but inhibition of 5-alpha-reductase and anti-inflammatory actions are proposed.

In summary, there is scientific evidence supporting the use of Cucurbita seeds or extracts for prostate health. However, the evidence is not robust enough to warrant a high rating, and more large-scale, high-quality trials are needed to confirm efficacy.

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