Evidence supporting the use of: Isoflavones
For the body system: Prostate

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Isoflavones, particularly those derived from soy (such as genistein and daidzein), have a history of traditional use and are commonly marketed as supplements for prostate health, especially in the context of benign prostatic hyperplasia (BPH) and prostate cancer risk reduction. The rationale is largely based on epidemiological observations: populations with high dietary intake of soy isoflavones, such as those in East Asia, tend to have lower rates of prostate cancer compared to Western populations. However, direct scientific evidence supporting the efficacy of isoflavones for prostate health is limited and inconsistent. Some in vitro and animal studies suggest that isoflavones may exert weak estrogen-like effects, potentially influencing hormone metabolism and cell growth in the prostate. A few small human studies have explored isoflavone supplementation for BPH symptoms or prostate cancer markers, but results have been mixed, with no clear clinical benefit established. Systematic reviews and meta-analyses generally conclude that there is insufficient high-quality evidence to recommend isoflavones as a treatment or preventive measure for prostate conditions. As such, while traditional use and epidemiological associations exist, robust scientific validation is lacking, resulting in a modest evidence rating.

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Products containing isoflavones

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