Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Pomegranate (Punica granatum) has been investigated for its potential benefits in supporting prostate health, particularly regarding prostate cancer and benign prostatic hyperplasia (BPH). Several preclinical studies have demonstrated that pomegranate extracts, juice, and polyphenols can inhibit the proliferation of prostate cancer cells and reduce inflammation in animal models. These effects are mainly attributed to the antioxidant and anti-inflammatory properties of pomegranate constituents such as ellagitannins and punicalagins.

A number of small-scale human clinical trials have also been conducted. Some studies suggest that pomegranate juice or extract may slow the rise of prostate-specific antigen (PSA) levels in men with prostate cancer, possibly delaying disease progression. However, most human data are preliminary, with methodological limitations such as small sample sizes, lack of placebo control, and short durations. Systematic reviews and meta-analyses generally conclude that while pomegranate is safe and shows promise in laboratory studies, there is insufficient clinical evidence to recommend it as a primary therapy for prostate conditions. Most authoritative health organizations do not formally endorse pomegranate for prostate health due to the need for more rigorous, large-scale trials.

In summary, the use of pomegranate to support prostate health is based on emerging scientific evidence, but its clinical efficacy remains unproven. Its use is better supported by laboratory and animal studies than by strong, consistent human trial data.

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