Evidence supporting the use of: Pygeum
For the body system: Prostate

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Pygeum (Prunus africana) is a traditional herbal remedy derived from the bark of the African cherry tree. Its primary use in modern supplements is for supporting prostate health, especially for symptoms associated with benign prostatic hyperplasia (BPH). There is scientific evidence supporting its efficacy: several randomized controlled trials and meta-analyses suggest that pygeum extract can modestly improve urinary symptoms related to BPH, such as nocturia, urine flow, and residual urine volume. The proposed mechanisms include anti-inflammatory effects, inhibition of prostatic fibroblast proliferation, and modulation of sex hormones.

A 2002 Cochrane review of 18 randomized controlled trials (involving 1,562 men) found that pygeum was associated with a moderate improvement in overall urinary symptoms and flow measures compared to placebo. However, the methodological quality of many studies was variable, and most were of short duration (less than 12 months). More recent research continues to suggest benefit, but large, high-quality, long-term studies are lacking. Pygeum is generally well tolerated, with mild gastrointestinal side effects reported in some cases.

In summary, while the traditional use of pygeum for urinary and prostate health is well documented, there is also a moderate level of scientific evidence supporting its role in managing mild-to-moderate symptoms of BPH. Nonetheless, more robust clinical trials are needed to confirm its long-term efficacy and safety.

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Other body systems supported by pygeum

Bladder
Male Reproductive System
Prostate
Urinary System