Relationship: Prostate and selenium

Evidence supporting the use of: Selenium
For the body system: Prostate

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenium is an essential trace mineral that has been studied for its role in prostate health, particularly in relation to prostate cancer risk. Scientific interest in selenium’s effects on the prostate was largely spurred by observational studies suggesting that higher selenium status might be associated with a reduced risk of prostate cancer. Selenium’s proposed mechanisms of action include its antioxidant properties, which may help protect prostate cells from oxidative damage, and its potential role in regulating cell proliferation and apoptosis.

However, large, well-designed randomized controlled trials have yielded mixed results. The most notable is the Selenium and Vitamin E Cancer Prevention Trial (SELECT), which found no significant reduction in prostate cancer risk with selenium supplementation and even suggested a potential increase in risk in certain subgroups. Other meta-analyses and systematic reviews have concluded that while selenium is essential for health, supplementation does not consistently demonstrate a protective effect against prostate cancer in men with adequate baseline selenium levels.

In summary, while selenium has a scientific basis for its use in supporting prostate health, especially in populations with low selenium status, current high-quality evidence does not robustly support supplementation for prostate disease prevention in the general population. The use of selenium for prostate support is therefore rated as having moderate (3/5) scientific evidence, with benefits likely limited to specific deficiencies rather than broad supplementation.

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Other ingredients that support Prostate

7-hydroxymatairesinol (HMR)
beta-sitosterol
sesame
boron
broccoli
campesterol
turmeric
diallyl trisulfide (DATS)
DIM (diindolylmethane)
epigallocatechin gallate (EGCG)
flaxseed
gamma tocopherol
genistein
gokhru
green tea
HMR lignan
indole-3-carbinol
lignans
lycopene
mixed carotenoids
nettle
parsley
phytosterols
plant sterols
pollen
pomegranate
pumpkin
pygeum
quercetin
saw palmetto
secoisolariciresinol diglucoside
selenium
soybean
sterols
stigmasterol
tomato
vitamin D
watermelon
zinc
bee pollen
lingzhi
Equol (proprietary)
hydrangea
herbal blend (proprietary)
Apigenin
Alchornea
Alpha phytosterol
Allium tuberosum
Anti-aromatase
Brassica
berry
Brazil nut
Ba Ji Tian
Bee products
Borassus aethiopum
Chinese Mountain Ant
Cucurbita
Cynomorium
Cruciferous
Crinum latifolium
Decursin
Daidzein
Dwarf Nettle
Ellagic Acid
Garlic
Isoflavones
Soy Protein
walnut

Other body systems supported by selenium

Blood
Brain
Circulatory System
Female Reproductive System
Glandular System
Hair
Heart
Immune System
Liver
Male Reproductive System
Mitochondria
Nails
Prostate
Reproductive System
Reproductive System
Skin
Testes
Testosterone
Thyroid Gland

Products containing selenium

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Evidence supporting the use of: Selenium
For the body system: Prostate

Table of Contents

Synopsis

Other ingredients that support Prostate

Other body systems supported by selenium

Products containing selenium

Health Concerns

Brands

Evidence supporting the use of: SeleniumFor the body system: Prostate

Table of Contents

Synopsis

Other ingredients that support Prostate

Other body systems supported by selenium

Products containing selenium

Evidence supporting the use of: Selenium
For the body system: Prostate