Evidence supporting the use of: Aminopeptidase
For the health condition: Protein Digestion (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Aminopeptidase is an enzyme involved in the proteolytic breakdown of proteins into amino acids by cleaving amino acids from the amino (N-) terminus of peptide chains. Its use in supporting or treating poor protein digestion is justified by scientific evidence. Aminopeptidases are naturally present in the small intestine and play a crucial role in the final stages of protein digestion, working alongside other proteases like trypsin, chymotrypsin, and carboxypeptidases. Supplementation with exogenous aminopeptidase, often as part of a broad-spectrum digestive enzyme formulation, has been shown to improve the digestion and absorption of dietary proteins, especially in individuals with pancreatic insufficiency, certain gastrointestinal disorders, or age-related decline in endogenous enzyme production.

Multiple studies have demonstrated that oral supplementation with enzyme preparations containing aminopeptidase can enhance protein hydrolysis, reduce the presence of large peptides in the gut, and increase amino acid absorption. For example, clinical research in patients with exocrine pancreatic insufficiency has found improved protein nutritional status and reduced gastrointestinal symptoms with enzyme supplementation. While most commercial enzyme blends contain a mixture of proteases, the specific role of aminopeptidase in completing the breakdown of peptides supports its inclusion in such products. Therefore, the use of aminopeptidase to support or treat poor protein digestion is scientifically valid, with a moderate to strong evidence base.

More about Aminopeptidase
More about Protein Digestion (poor)

Other health conditions supported by Aminopeptidase

Inflammation
Protein Digestion (poor)

Products containing Aminopeptidase

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