Evidence supporting the use of: Ananain
For the health condition: Protein Digestion (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ananain is a cysteine protease enzyme found in pineapple stems, similar to the better-known bromelain. It is capable of breaking down proteins into smaller peptides and amino acids. Scientific studies have demonstrated the proteolytic activity of ananain in vitro, confirming its ability to digest protein substrates. The rationale for using enzymes like ananain to support or treat poor protein digestion is based on their capacity to supplement endogenous digestive enzymes, particularly in individuals with pancreatic insufficiency or other digestive disorders that impair protein breakdown.

While bromelain has been more extensively studied and used commercially for digestive health, ananain shares many of its biochemical properties. Some research has shown that extracts containing ananain can enhance protein digestion in simulated gastric environments and animal models. However, direct clinical trials focusing specifically on ananain for human protein digestion are limited, so most of the evidence comes from biochemical and preclinical studies, as well as extrapolation from bromelain research.

In summary, there is reasonable scientific rationale and some supportive evidence for the use of ananain to aid protein digestion, but high-quality clinical trials in humans are lacking. Thus, its use is scientifically plausible and supported by moderate (but not robust) evidence, earning a score of 3 out of 5.

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Products containing Ananain

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