Evidence supporting the use of: Liquid liver fractions
For the health condition: Protein Digestion (poor)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Liquid liver fractions have a long history of use in traditional medicine and early nutritional therapy, particularly in the mid-20th century, as a tonic for general health and as a supportive supplement for individuals with poor protein digestion or malnutrition. The rationale was that liver is a nutrient-dense organ, providing not only proteins but also a wide range of vitamins (such as B12 and folate), minerals (like iron and zinc), and naturally occurring enzymes and cofactors believed to support digestive and metabolic functions. In the context of poor protein digestion, traditional practitioners theorized that liquid liver fractions could provide easily assimilable forms of amino acids and peptides, as well as stimulating the body's own digestive processes due to its nutrient density.

However, while these traditions underpin the use of liver extracts in some nutritional supplements today, there is limited direct scientific evidence supporting their effectiveness specifically for improving protein digestion. Some animal studies and early clinical reports suggested that liver extracts might have general tonic or hematinic effects, but robust clinical trials in humans for protein digestion are lacking. Modern digestive enzyme supplements usually rely on pancreatic enzymes or microbial proteases for direct support of protein breakdown. Therefore, the use of liquid liver fractions for poor protein digestion is primarily justified by tradition and historical use, not by strong scientific validation.

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Products containing liquid liver fractions

Integrative Therapeutics Iron Complex