Evidence supporting the use of: Alfalfa
For the health condition: Psoriasis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Alfalfa (Medicago sativa) has been traditionally used in various herbal medicine systems for its purported health benefits, including as a remedy for skin conditions like psoriasis. Early herbalists and naturopathic practitioners suggested that alfalfa, being rich in vitamins (notably vitamin K, C, and some B vitamins), minerals (such as calcium, magnesium, and potassium), and chlorophyll, could help “cleanse the blood” and support skin health. However, this rationale is primarily anecdotal and rooted in the concept of “internal cleansing” that was popular in traditional Western herbalism and naturopathy during the late 19th and early 20th centuries.

Despite its traditional use, there is extremely limited scientific research specifically evaluating alfalfa’s efficacy for psoriasis. No high-quality clinical trials or substantial preclinical studies have demonstrated a clear benefit of alfalfa supplementation or topical application in psoriasis patients. In fact, some case reports suggest that alfalfa may even trigger or worsen autoimmune conditions, including lupus-like syndromes, due to its L-canavanine content.

In summary, while alfalfa has a minor traditional background in treating psoriasis, there is little to no scientific evidence supporting its effectiveness, and it is not widely recommended by dermatologists or evidence-based practitioners for this condition. Use should be approached with caution, especially in people with autoimmune tendencies.

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Agrimonia pilosa
Alfalfa
algal oil
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alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
Andrographis
andrographolide
apigenin
apple cider vinegar
argan nut oil
astragalin
Aureobasidium pullulans
avocado
babchi
baicalein
baicalin
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banyan
Baphicacanthus cusia
Barleria
bee propolis
beta-glucan
Bifidobacterium breve
Bifidobacterium longum
birch
black currant
black walnut
Borassus aethiopum
Boswellia
Boswellic Acid
bupleurum falcatum
burdock
butyrate triglyceride
caffeic Acid
cannabidiol
Centella asiatica
Centella triterpenes
Chinese salvia root
chirata
Cistus
Cnidium
cod liver oil
copaiba oil
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
emu oil
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethyl linoleate
European Elder
ferulic acid
Ficus religiosa
fish protein
frankincense
fumaric acid
gallic acid
gamma linolenic acid (GLA)
Glucosylceramide
Glycolic acid
Glycyrrhetinic acid
Glycyrrhizin
gooseberry
gotu kola
green tea
Hellebore
henna
hyaluronic acid
Hyperoside
isoliquiritigenin
jojoba oil
Kaempferol
knotweed
lactiplantibacillus plantarum
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus salivarius
Ledebouriella
lingzhi
linoleic acid (LA)
linseed oil
liverwort
loquat
luteolin
Lycium
magnesium
Marine fat
Marshmallow
melaleuca alternifolia
mixed carotenoids
Morus
Mucilage
Mulberry
Naringenin
Nettle
Niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
perilla
PhosphatidylGlycerol
phospholipids
Piperine
Polypodium
polyunsaturated fat
pomegranate
quercetin
resveratrol
rockweed
Rubia cordifolia
Salmon Oil
Sanguisorba
Sargassum
sarsaparilla
seaweed
Semecarpus anacardium
Slippery Elm
specialized pro-resolving mediators (SPMs)
spirulina
sunflower
Tea Tree Oil
Thuja
turmeric
vegetable oil
Verbascoside
vitamin A
vitamin D
vitamin D3
vitamin E
Walnut
wheat grass
Withanolides
Xanthone
Xanthophyll
Xanthorrhizol
Zinc