Evidence supporting the use of: Apigenin
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Apigenin is a natural flavonoid found in various plants, including parsley, celery, and chamomile. Its use in supporting or treating psoriasis is based on emerging scientific evidence rather than longstanding traditional application. Preclinical studies, primarily conducted in vitro (cell cultures) and in animal models, have demonstrated that apigenin exhibits anti-inflammatory, antioxidant, and immunomodulatory effects, which are relevant to the pathophysiology of psoriasis. For example, research has shown that apigenin can inhibit the production of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-17, which play key roles in the development and progression of psoriatic lesions (Li et al., 2018). Additionally, apigenin has been reported to suppress the activation of NF-κB, a transcription factor involved in inflammation and immune responses. However, there is a lack of robust clinical data in humans directly evaluating apigenin for psoriasis treatment. No large-scale randomized controlled trials have been published to date. The evidence for apigenin’s efficacy in psoriasis is therefore limited to preclinical studies, and more research is needed before it can be recommended as a standard or adjunctive therapy. In summary, while there is a scientific basis for investigating apigenin in psoriasis, current evidence supporting its use is preliminary and not yet sufficient for clinical recommendations.

More about apigenin
More about Psoriasis

Other ingredients used for Psoriasis

Agrimonia pilosa
Alfalfa
algal oil
Aloe vera
Alpha hydroxy acids
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
Andrographis
andrographolide
apigenin
apple cider vinegar
argan nut oil
astragalin
Aureobasidium pullulans
avocado
babchi
baicalein
baicalin
Baikal Skullcap
banyan
Baphicacanthus cusia
Barleria
bee propolis
beta-glucan
Bifidobacterium breve
Bifidobacterium longum
birch
black currant
black walnut
Borassus aethiopum
Boswellia
Boswellic Acid
bupleurum falcatum
burdock
butyrate triglyceride
caffeic Acid
cannabidiol
Centella asiatica
Centella triterpenes
Chinese salvia root
chirata
Cistus
Cnidium
cod liver oil
copaiba oil
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
emu oil
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethyl linoleate
European Elder
ferulic acid
Ficus religiosa
fish protein
frankincense
fumaric acid
gallic acid
gamma linolenic acid (GLA)
Glucosylceramide
Glycolic acid
Glycyrrhetinic acid
Glycyrrhizin
gooseberry
gotu kola
green tea
Hellebore
henna
hyaluronic acid
Hyperoside
isoliquiritigenin
jojoba oil
Kaempferol
knotweed
lactiplantibacillus plantarum
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus salivarius
Ledebouriella
lingzhi
linoleic acid (LA)
linseed oil
liverwort
loquat
luteolin
Lycium
magnesium
Marine fat
Marshmallow
melaleuca alternifolia
mixed carotenoids
Morus
Mucilage
Mulberry
Naringenin
Nettle
Niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
perilla
PhosphatidylGlycerol
phospholipids
Piperine
Polypodium
polyunsaturated fat
pomegranate
quercetin
resveratrol
rockweed
Rubia cordifolia
Salmon Oil
Sanguisorba
Sargassum
sarsaparilla
seaweed
Semecarpus anacardium
Slippery Elm
specialized pro-resolving mediators (SPMs)
spirulina
sunflower
Tea Tree Oil
Thuja
turmeric
vegetable oil
Verbascoside
vitamin A
vitamin D
vitamin D3
vitamin E
Walnut
wheat grass
Withanolides
Xanthone
Xanthophyll
Xanthorrhizol
Zinc

Products containing apigenin

We currently have no products on Vitabase that contain this ingredient.