Evidence supporting the use of: Baikal Skullcap
For the health condition: Psoriasis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Baikal Skullcap (Scutellaria baicalensis) has a long history of use in traditional Chinese medicine (TCM), where it is known as "Huang Qin." It is traditionally employed for its anti-inflammatory and detoxifying properties and has been used for various inflammatory skin conditions, including psoriasis. The rationale in TCM for using Baikal Skullcap in psoriasis often centers on its ability to "clear heat" and "dry dampness," which are metaphoric diagnoses within TCM theory.

Modern scientific studies have identified that the plant contains flavonoids such as baicalin, baicalein, and wogonin, which exhibit anti-inflammatory and antioxidant effects in vitro and in animal models. Some preclinical research suggests these compounds may modulate immune function, inhibit pro-inflammatory cytokines, and reduce oxidative stress, factors implicated in the pathogenesis of psoriasis. However, there is a lack of high-quality clinical trials directly examining its efficacy for psoriasis in humans. Most supportive evidence is anecdotal or based on extrapolation from general anti-inflammatory effects or studies in other inflammatory skin conditions.

In summary, the use of Baikal Skullcap for psoriasis is primarily justified by traditional use, with limited but suggestive preclinical evidence. Robust clinical validation is lacking, so its efficacy and safety for this specific condition remain unproven by modern scientific standards.

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