Evidence supporting the use of: Bupleurum falcatum
For the health condition: Psoriasis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bupleurum falcatum is a medicinal herb widely used in traditional Chinese medicine (TCM), particularly as a component of formulas aimed at "clearing heat" and "soothing the liver." In TCM practice, Bupleurum is often included in multi-herb prescriptions for various inflammatory and autoimmune conditions, including skin disorders like psoriasis. The traditional rationale is based on the belief that Bupleurum helps to harmonize the body's internal organs and reduce internal heat, which is thought to manifest as skin eruptions.

However, scientific validation for Bupleurum falcatum specifically in the treatment of psoriasis is extremely limited. While the plant contains active compounds such as saikosaponins that have shown anti-inflammatory and immunomodulatory effects in preclinical studies, there is little direct clinical research evaluating its efficacy for psoriasis in humans. Some animal and cell studies suggest potential anti-inflammatory and hepatoprotective effects, but these are not specific to psoriasis and are often not replicated in high-quality human trials.

In summary, while Bupleurum falcatum is traditionally used in TCM as part of multi-herb formulas for inflammatory skin conditions like psoriasis, the evidence for its effectiveness is primarily anecdotal and traditional, with only limited and indirect scientific support. Thus, its use for psoriasis should be considered as based more on tradition than solid scientific validation.

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