Evidence supporting the use of: Caffeic Acid
For the health condition: Psoriasis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Caffeic acid is a naturally occurring polyphenol found in many plants, especially coffee, fruits, and some herbs. Its potential use in supporting or treating psoriasis is based primarily on its anti-inflammatory and antioxidant properties, which have been demonstrated in preclinical (in vitro and animal) studies. Several studies have shown that caffeic acid can inhibit pro-inflammatory cytokines and reduce oxidative stress, both of which play significant roles in the pathogenesis of psoriasis. For example, research published in Biomedicine & Pharmacotherapy (2017) and other journals has reported that caffeic acid and its derivatives can suppress key inflammatory pathways such as NF-κB and decrease the production of cytokines like TNF-α, IL-1β, and IL-6. However, there are no robust clinical trials in humans specifically evaluating caffeic acid for the treatment or support of psoriasis. The evidence is thus limited to laboratory and animal studies, and while promising, does not yet support its use as a standard therapy. There is no substantial record of traditional use of caffeic acid specifically for psoriasis, though it is present in many traditionally used medicinal plants. Overall, the evidence base is still preliminary and further research, especially human clinical trials, is needed to confirm its efficacy and safety for psoriasis management.
Other ingredients used for Psoriasis
Agrimonia pilosaAlfalfa
algal oil
Aloe vera
Alpha hydroxy acids
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
Andrographis
andrographolide
apigenin
apple cider vinegar
argan nut oil
astragalin
Aureobasidium pullulans
avocado
babchi
baicalein
baicalin
Baikal Skullcap
banyan
Baphicacanthus cusia
Barleria
bee propolis
beta-glucan
Bifidobacterium breve
Bifidobacterium longum
birch
black currant
black walnut
Borassus aethiopum
Boswellia
Boswellic Acid
bupleurum falcatum
burdock
butyrate triglyceride
caffeic Acid
cannabidiol
Centella asiatica
Centella triterpenes
Chinese salvia root
chirata
Cistus
Cnidium
cod liver oil
copaiba oil
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
emu oil
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethyl linoleate
European Elder
ferulic acid
Ficus religiosa
fish protein
frankincense
fumaric acid
gallic acid
gamma linolenic acid (GLA)
Glucosylceramide
Glycolic acid
Glycyrrhetinic acid
Glycyrrhizin
gooseberry
gotu kola
green tea
Hellebore
henna
hyaluronic acid
Hyperoside
isoliquiritigenin
jojoba oil
Kaempferol
knotweed
lactiplantibacillus plantarum
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Lactobacillus rhamnosus
Lactobacillus salivarius
Ledebouriella
lingzhi
linoleic acid (LA)
linseed oil
liverwort
loquat
luteolin
Lycium
magnesium
Marine fat
Marshmallow
melaleuca alternifolia
mixed carotenoids
Morus
Mucilage
Mulberry
Naringenin
Nettle
Niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
perilla
PhosphatidylGlycerol
phospholipids
Piperine
Polypodium
polyunsaturated fat
pomegranate
quercetin
resveratrol
rockweed
Rubia cordifolia
Salmon Oil
Sanguisorba
Sargassum
sarsaparilla
seaweed
Semecarpus anacardium
Slippery Elm
specialized pro-resolving mediators (SPMs)
spirulina
sunflower
Tea Tree Oil
Thuja
turmeric
vegetable oil
Verbascoside
vitamin A
vitamin D
vitamin D3
vitamin E
Walnut
wheat grass
Withanolides
Xanthone
Xanthophyll
Xanthorrhizol
Zinc