Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabigerolic acid (CBGA) is a precursor cannabinoid found in Cannabis sativa. Recent scientific research has begun to explore its therapeutic potential, including for skin disorders such as psoriasis. Laboratory studies have suggested that CBGA and other cannabinoids may exert anti-inflammatory effects by interacting with the endocannabinoid system, particularly through the modulation of CB1 and CB2 receptors, which are present in skin cells. In vitro experiments have demonstrated that CBGA can inhibit the proliferation of keratinocytes—the overproduction of which is a hallmark of psoriasis. Additionally, CBGA has shown the ability to reduce the production of pro-inflammatory cytokines, which play a key role in the pathogenesis of psoriasis. However, it is important to note that the bulk of this evidence comes from preclinical studies, including cell culture and animal models. There are currently no published clinical trials directly evaluating the efficacy or safety of CBGA in human patients with psoriasis. While the mechanistic data are promising and provide a scientific rationale for further exploration, clinical validation is lacking. Therefore, the use of CBGA for psoriasis is currently supported by preliminary scientific evidence, but not by robust clinical data or traditional use.

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Other ingredients used for Psoriasis

Alfalfa
algal oil
Aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (Vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
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Apigenin
Andrographolide
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Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
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Cnidium
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Ficus religiosa
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vegetable oil
Verbascoside
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walnut
Xanthophyll
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Other health conditions supported by Cannabigerolic acid

Acne
Arthritis
Inflammation
Inflammatory Bowel Disorders
Psoriasis

Products containing Cannabigerolic acid

We currently have no products on Vitabase that contain this ingredient.