Copaiba oil, derived from the resin of the Copaifera tree native to South America, has a long history of traditional use in folk medicine, particularly in Brazil. It has been applied topically for various skin conditions, including psoriasis, due to its reputed anti-inflammatory and wound-healing properties. The traditional rationale is largely based on anecdotal evidence and historic ethnobotanical records, rather than robust clinical trials.

Scientific studies on copaiba oil have demonstrated that its main active component, β-caryophyllene, possesses anti-inflammatory and antimicrobial effects in vitro and in animal models. However, there is a lack of well-designed clinical trials specifically evaluating its efficacy and safety for psoriasis in humans. Most published research focuses on its general anti-inflammatory actions or its use in other dermatological conditions.

In summary, while copaiba oil is traditionally used to support the treatment of psoriasis and there is some basic scientific rationale for its potential benefit, there is insufficient clinical evidence to confirm its effectiveness for this condition. Its use is primarily justified by traditional practices rather than scientific validation.