Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid found primarily in fish oil. Its use for psoriasis is justified by scientific rather than traditional evidence, though the strength of evidence is modest. Psoriasis is a chronic inflammatory skin disease characterized by overactive immune responses and increased production of pro-inflammatory cytokines. Omega-3 fatty acids like DHA have well-documented anti-inflammatory effects, which has led researchers to investigate their role in managing inflammatory conditions, including psoriasis.

Several small clinical studies and meta-analyses have looked at the effects of omega-3 supplementation (mainly EPA and DHA from fish oil) on psoriasis. Some studies have demonstrated modest improvements in disease severity, scaling, and erythema in patients treated with omega-3 supplements compared to placebo. The proposed mechanism involves DHA's ability to reduce production of inflammatory eicosanoids and cytokines, and to alter immune cell function.

However, the evidence is not robust: many studies have methodological limitations such as small sample sizes, short duration, or use of mixed omega-3s rather than DHA alone. A 2020 review in the Journal of Dermatological Treatment concluded that while there is some evidence supporting omega-3s in psoriasis, results are inconsistent and further high-quality trials are needed. DHA is not considered a first-line therapy but may be used as an adjunct to standard treatments. Overall, scientific evidence exists but is limited, justifying a moderate evidence rating.

More about DHA (docosahexaeonic acid)
More about Psoriasis

Other ingredients used for Psoriasis

Other health conditions supported by DHA (docosahexaeonic acid)

Products containing DHA (docosahexaeonic acid)

Thorne Advanced DHA
Vitabase Brain Support
Vitabase Complete Essential Fatty Acids
Pure Encapsulations DHA Ultimate
Pure Encapsulations DHA Ultimate
Pure Encapsulations EFA Essentials
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations EPA/DHA
Pure Encapsulations EPA/DHA essentials 1,000 mg
Pure Encapsulations EPA/DHA essentials 1,000 mg
Vitabase EPA / DHA Omega-3
Pure Encapsulations EPA/DHA with Lemon
Pure Encapsulations EPA Ultimate
Klean Athlete Klean Omega ™
Douglas Laboratories Krill Oil
Pure Encapsulations Krill-Plex
Pure Encapsulations Krill-Plex
Metagenics MetaKids DHA
Metagenics MetaKids Nutrition Powder Chocolate
Metagenics MetaKids Nutrition Powder Vanilla
Pure Encapsulations NeuroMood Pure Pack
Pure Encapsulations O.N.E.™ Omega
Pure Encapsulations O.N.E.™ Omega
Thorne Omega-3 w/ CoQ10
Thorne Omega Superb Lemon Berry
Metagenics OmegaGenics Algae EPA-DHA 300 mg
Metagenics OmegaGenics EPA DHA 2400 Fish Oil
Metagenics OmegaGenics EPA-DHA 300 Lemon Lime
Metagenics OmegaGenics Fish Oil EPA-DHA 1000 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 1000 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 500 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 500 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 720 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 720 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 720 mg
Metagenics OmegaGenics Fish Oil Mega 10®
Metagenics OmegaGenics Neuro 1000 mg
Designs For Health OmegAvail™ Hi-Po
Designs For Health OmegAvail™ Hi-Po
Designs For Health OmegAvail™ Hi-Po Liquid
Designs For Health OmegAvail™ Liquid
Designs For Health OmegAvail™ Synergy
Designs For Health OmegAvail™ Synergy
Designs For Health OmegAvail™ TG1000
Designs For Health OmegAvail™ Ultra
Designs For Health OmegAvail™ Ultra
Designs For Health OmegAvail™ Ultra DHA
Designs For Health OmegAvail™ Ultra with Vitamin D3, K1 and K2
Douglas Laboratories Opti-EPA 500 ™ Cholesterol Free
Douglas Laboratories Opti-EPA 500 ™ Cholesterol Free
Metagenics PlusOne® Daily Prenatal Packs
Thorne Prenatal DHA
Pure Encapsulations Pro-Resolve Omega
Thorne Pro-Resolving Mediators
Integrative Therapeutics Pure Omega HP
Integrative Therapeutics Pure Omega Liquid
Integrative Therapeutics Pure Omega Ultra HP
Pure Encapsulations PureNutrients EPA/DHA
Douglas Laboratories QÜELL® FISH OIL DHA Ultra SPM
Douglas Laboratories QUELL Fish Oil ® - EPA/DHA Plus D
Metagenics SPM Active
Thorne Super EPA
Thorne Super EPA NSF
Thorne Super EPA Pro
Vitabase Super Omega-3
Douglas Laboratories Ultra G.L.A. Borage Oil
Douglas Laboratories Ultra G.L.A. Borage Oil
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations VisionPro EPA/DHA/GLA
Pure Encapsulations VisionPro EPA/DHA/GLA
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs
Designs For Health XanthOmega™ Krill Oil