Evidence supporting the use of: Docosahexaenoic Acid
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Docosahexaenoic Acid (DHA) is an omega-3 polyunsaturated fatty acid primarily found in fish oil. Its use in psoriasis is based on scientific research investigating the anti-inflammatory properties of omega-3 fatty acids, including DHA. Psoriasis is a chronic, immune-mediated skin condition characterized by hyperproliferation of keratinocytes and inflammation. Some clinical studies suggest that omega-3 fatty acids can reduce the severity of psoriasis symptoms, potentially by modulating inflammatory cytokines such as TNF-α, IL-1β, and IL-6, which are implicated in the pathogenesis of psoriasis.

However, most of the evidence comes from studies using mixed omega-3 supplementation (e.g., EPA and DHA together) rather than DHA alone. For example, a 2014 systematic review (Am J Clin Dermatol) found modest benefit for omega-3 supplementation in psoriasis but noted heterogeneity in study design, dosage, and formulations. There is limited direct evidence for DHA as a standalone intervention. Most clinical trials have small sample sizes and short durations, and not all have shown significant clinical improvements.

In summary, while there is some scientific rationale and modest clinical evidence supporting the use of DHA (as part of omega-3 fatty acids) in managing psoriasis, the strength of the evidence is limited. DHA is not considered a primary or stand-alone treatment, and further large, well-controlled studies are needed to clarify its specific role.

More about Docosahexaenoic Acid
More about Psoriasis

Other ingredients used for Psoriasis

Alfalfa
algal oil
Aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (Vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
Fumaric Acid
Ficus religiosa
Frankincense
Gallic Acid
Glycolic acid
Glucosylceramide
Glycyrrhetinic Acid
Glycyrrhizin
Hyperoside
Hellebore
Henna
isoliquiritigenin
Jojoba Oil
Kaempferol
Lycium
Loquat
Lactobacillus plantarum
Ledebouriella
Linseed Oil
Liverwort
Mucilage
Marine fat
Naringenin
Osthole
Piperine
Polyunsaturated Fat
Polypodium
PhosphatidylGlycerol
Paeoniflorin
Palmitoylethanolamide (PEA)
Rockweed
Sanguisorba
Salmon Oil
Slippery Elm
Semecarpus anacardium
Sulfur
Sargassum
Thuja
Tea Tree Oil
vegetable oil
Verbascoside
Withanolides
walnut
Xanthophyll
Xanthorrhizol
Xanthone

Products containing Docosahexaenoic Acid

We currently have no products on Vitabase that contain this ingredient.