Evidence supporting the use of: Ethyl Linoleate
For the health condition: Psoriasis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Ethyl linoleate, an ester derivative of linoleic acid (an omega-6 polyunsaturated fatty acid), has some scientific backing for its potential in supporting or treating psoriasis, though the evidence is limited and primarily preclinical. Linoleic acid and its derivatives are known for their anti-inflammatory properties and their role in maintaining skin barrier integrity. In animal models and in vitro studies, ethyl linoleate has demonstrated the capacity to reduce inflammation and modulate immune responses, which are key contributors to psoriasis pathogenesis. One study (Kim et al., 2008) reported that topical ethyl linoleate significantly inhibited the expression of inflammatory markers in a mouse model of psoriasis-like skin inflammation. Additionally, linoleic acid esters have been shown to improve skin hydration and barrier function, which may be beneficial for psoriatic lesions characterized by dryness and scaling. However, clinical evidence directly supporting the use of ethyl linoleate in human psoriasis patients is lacking. Most available studies are preclinical, and there are no large-scale, peer-reviewed clinical trials confirming efficacy in humans. Therefore, while the underlying mechanisms and preliminary data suggest potential benefit, the overall evidence remains modest, and further research is necessary to establish its therapeutic value for psoriasis.
Other ingredients used for Psoriasis
alfalfaalgal oil
aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
walnut