Evidence supporting the use of: Glucosylceramide
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glucosylceramide, a glycosphingolipid found in plants and animals, has been studied for its role in maintaining skin barrier function and hydration. Psoriasis is characterized by disrupted skin barrier, inflammation, and increased transepidermal water loss. Limited scientific evidence suggests that oral or topical supplementation with glucosylceramide may improve skin barrier integrity and hydration in healthy individuals or those with dry skin conditions. Some small-scale clinical studies and animal models have shown that plant-derived glucosylceramides can enhance ceramide levels in the stratum corneum and improve skin moisture.

However, direct evidence for the effectiveness of glucosylceramide in treating or supporting psoriasis specifically is sparse. Most available studies do not focus on psoriatic patients but rather on general skin health or xerosis. A few preclinical studies suggest that improving the skin barrier with ceramide-related lipids could help alleviate symptoms in skin diseases like psoriasis, but robust clinical trials in psoriatic populations are lacking. Therefore, while the rationale is scientifically plausible and there is some early evidence supporting a beneficial role in skin barrier function, the evidence supporting glucosylceramide as a treatment or supportive intervention for psoriasis is limited and rated low.

In summary, glucosylceramide is not a standard or widely recommended therapy for psoriasis, and more targeted research is required to establish its efficacy for this condition.

More about Glucosylceramide
More about Psoriasis

Other health conditions supported by Glucosylceramide

Inflammation
Psoriasis
Skin Care (general)

Products containing Glucosylceramide

We currently have no products on Vitabase that contain this ingredient.