Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glucosylceramide, a glycosphingolipid found in plants and animals, has been studied for its role in maintaining skin barrier function and hydration. Psoriasis is characterized by disrupted skin barrier, inflammation, and increased transepidermal water loss. Limited scientific evidence suggests that oral or topical supplementation with glucosylceramide may improve skin barrier integrity and hydration in healthy individuals or those with dry skin conditions. Some small-scale clinical studies and animal models have shown that plant-derived glucosylceramides can enhance ceramide levels in the stratum corneum and improve skin moisture.

However, direct evidence for the effectiveness of glucosylceramide in treating or supporting psoriasis specifically is sparse. Most available studies do not focus on psoriatic patients but rather on general skin health or xerosis. A few preclinical studies suggest that improving the skin barrier with ceramide-related lipids could help alleviate symptoms in skin diseases like psoriasis, but robust clinical trials in psoriatic populations are lacking. Therefore, while the rationale is scientifically plausible and there is some early evidence supporting a beneficial role in skin barrier function, the evidence supporting glucosylceramide as a treatment or supportive intervention for psoriasis is limited and rated low.

In summary, glucosylceramide is not a standard or widely recommended therapy for psoriasis, and more targeted research is required to establish its efficacy for this condition.

More about Glucosylceramide
More about Psoriasis

Other ingredients used for Psoriasis

Agrimonia pilosa
Alfalfa
algal oil
Aloe vera
Alpha hydroxy acids
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
Andrographis
andrographolide
apigenin
apple cider vinegar
argan nut oil
astragalin
Aureobasidium pullulans
avocado
babchi
baicalein
baicalin
Baikal Skullcap
banyan
Baphicacanthus cusia
Barleria
bee propolis
beta-glucan
Bifidobacterium breve
Bifidobacterium longum
birch
black currant
black walnut
Borassus aethiopum
Boswellia
Boswellic Acid
bupleurum falcatum
burdock
butyrate triglyceride
caffeic Acid
cannabidiol
Centella asiatica
Centella triterpenes
Chinese salvia root
chirata
Cistus
Cnidium
cod liver oil
copaiba oil
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
emu oil
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethyl linoleate
European Elder
ferulic acid
Ficus religiosa
fish protein
frankincense
fumaric acid
gallic acid
gamma linolenic acid (GLA)
Glucosylceramide
Glycolic acid
Glycyrrhetinic acid
Glycyrrhizin
gooseberry
gotu kola
green tea
Hellebore
henna
hyaluronic acid
Hyperoside
isoliquiritigenin
jojoba oil
Kaempferol
knotweed
lactiplantibacillus plantarum
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus salivarius
Ledebouriella
lingzhi
linoleic acid (LA)
linseed oil
liverwort
loquat
luteolin
Lycium
magnesium
Marine fat
Marshmallow
melaleuca alternifolia
mixed carotenoids
Morus
Mucilage
Mulberry
Naringenin
Nettle
Niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
perilla
PhosphatidylGlycerol
phospholipids
Piperine
Polypodium
polyunsaturated fat
pomegranate
quercetin
resveratrol
rockweed
Rubia cordifolia
Salmon Oil
Sanguisorba
Sargassum
sarsaparilla
seaweed
Semecarpus anacardium
Slippery Elm
specialized pro-resolving mediators (SPMs)
spirulina
sunflower
Tea Tree Oil
Thuja
turmeric
vegetable oil
Verbascoside
vitamin A
vitamin D
vitamin D3
vitamin E
Walnut
wheat grass
Withanolides
Xanthone
Xanthophyll
Xanthorrhizol
Zinc

Other health conditions supported by Glucosylceramide

Inflammation
Psoriasis
Skin Care (general)

Products containing Glucosylceramide

We currently have no products on Vitabase that contain this ingredient.