Evidence supporting the use of: Hyperoside
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hyperoside is a flavonoid glycoside found in various medicinal plants, such as Hypericum perforatum (St. John’s Wort) and Crataegus species. Its use in supporting or treating psoriasis has some preliminary scientific basis, though clinical evidence in humans is lacking.

Recent in vitro and animal studies have explored hyperoside’s anti-inflammatory and antioxidant activities, which are relevant to the pathogenesis of psoriasis. For example, a study by Sun et al. (2020) in Frontiers in Pharmacology demonstrated that hyperoside suppressed inflammatory cytokine production in keratinocytes and reduced skin inflammation in a mouse model of psoriasis-like dermatitis. The proposed mechanisms involve inhibition of the NF-κB and MAPK signaling pathways, both of which are implicated in psoriasis pathology.

However, these findings are primarily preclinical. There are no published randomized controlled trials or substantial human data supporting the efficacy of hyperoside in psoriasis patients. Traditional or ethnobotanical use of hyperoside-containing plants for psoriasis is also not well-documented.

In summary, the use of hyperoside for psoriasis is scientifically plausible based on cellular and animal data, but the current level of evidence remains low (rated 2/5). More rigorous clinical trials are needed to establish its safety and efficacy in humans with psoriasis.

More about Hyperoside
More about Psoriasis

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argan nut oil
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beta-glucan
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black walnut
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bupleurum falcatum
burdock
butyrate triglyceride
caffeic Acid
cannabidiol
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Centella triterpenes
Chinese salvia root
chirata
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cod liver oil
copaiba oil
curcumin
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DHA (docosahexaenoic acid)
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
emu oil
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethyl linoleate
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ferulic acid
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fish protein
frankincense
fumaric acid
gallic acid
gamma linolenic acid (GLA)
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Glycolic acid
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Glycyrrhizin
gooseberry
gotu kola
green tea
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henna
hyaluronic acid
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isoliquiritigenin
jojoba oil
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knotweed
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linoleic acid (LA)
linseed oil
liverwort
loquat
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mixed carotenoids
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oleanolic acid
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Products containing Hyperoside

We currently have no products on Vitabase that contain this ingredient.