Evidence supporting the use of: PhosphatidylGlycerol
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phosphatidylglycerol (PG) has recently gained attention in dermatological research, particularly regarding its potential role in treating inflammatory skin diseases such as psoriasis. The scientific rationale for its use is primarily based on preclinical studies, including cell culture and animal models, rather than extensive clinical trials in humans. Notably, a 2017 study by Raghu et al. (J Invest Dermatol, 2017) demonstrated that topical application of PG reduced inflammation and normalized keratinocyte proliferation in a mouse model of psoriasis. The proposed mechanism involves PG modulating toll-like receptor (TLR) signaling pathways, which are known to be involved in the pathogenesis of psoriasis by promoting inflammation and dysregulated skin cell growth.

However, as of 2024, there is a lack of robust human clinical trial data supporting the efficacy or safety of PG for psoriasis treatment. The evidence supporting its use comes primarily from laboratory and animal studies, which, while promising, do not guarantee similar results in humans. PG is not a traditional remedy for psoriasis, nor is it found in standard clinical guidelines. At present, its use is considered experimental, and further research is needed to establish its therapeutic value in human patients with psoriasis.

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Other health conditions supported by PhosphatidylGlycerol

Inflammation
Psoriasis

Products containing PhosphatidylGlycerol

We currently have no products on Vitabase that contain this ingredient.