Evidence supporting the use of: Phospholipid
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phospholipids have some scientific rationale for use in the management of psoriasis, though their clinical evidence is limited and not robust. Phospholipids are essential components of cell membranes and play a significant role in maintaining skin barrier integrity and modulating inflammatory responses. In psoriasis, the skin barrier is often dysfunctional, and there is heightened inflammation. Some preclinical studies and small clinical investigations have explored the topical or oral use of phospholipids (such as phosphatidylcholine) either as active ingredients or as carriers to improve drug delivery in psoriasis treatments. These studies suggest that phospholipids may help restore the skin barrier and reduce inflammation by influencing cytokine production and oxidative stress. However, large-scale, randomized controlled trials demonstrating the efficacy of phospholipids alone as a treatment for psoriasis are lacking. Most research focuses on their supportive role in formulations or as adjuncts rather than as primary therapeutic agents. There is no strong traditional use of phospholipids for psoriasis, and the scientific evidence, while promising at a mechanistic level, is not yet conclusive. Thus, on the evidence scale, phospholipids score a 2, reflecting preliminary scientific support but insufficient clinical validation for routine use in treating psoriasis.

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Products containing phospholipid

We currently have no products on Vitabase that contain this ingredient.