Evidence supporting the use of: Reishi
For the health condition: Psoriasis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi (Ganoderma lucidum) has a long history of use in traditional Chinese medicine as a general health tonic and immunomodulator. Its use in the context of psoriasis is primarily based on traditional practices rather than robust scientific validation. Historically, Reishi has been used to 'purify the blood', reduce inflammation, and support immune balance—concepts relevant to the pathophysiology of psoriasis, which is an immune-mediated skin condition. Some traditional practitioners recommend Reishi to soothe chronic skin conditions, including psoriasis, owing to its purported anti-inflammatory and immunomodulatory properties.

On the scientific front, there are limited studies directly examining Reishi's efficacy for psoriasis. Laboratory and animal studies suggest Reishi extracts can modulate immune responses and reduce inflammation, mechanisms theoretically relevant to psoriasis. For example, certain polysaccharides and triterpenoids found in Reishi have demonstrated anti-inflammatory effects and immunoregulatory activity in preclinical models. However, there is a lack of well-controlled human clinical trials specifically investigating Reishi for psoriasis. The available evidence is therefore largely extrapolated from broader studies on inflammation and immunity rather than psoriasis itself.

In summary, Reishi’s use for psoriasis is justified predominantly by traditional use, with some preliminary scientific rationale but insufficient direct clinical evidence. The overall strength of evidence is low (2/5), warranting caution and further research before it can be recommended as a reliable adjunct or alternative therapy for psoriasis.

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Products containing Reishi

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