Evidence supporting the use of: Resveratrol
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Resveratrol, a polyphenolic compound found in grapes, berries, and peanuts, has attracted attention for its anti-inflammatory and antioxidant properties. In the context of psoriasis, there is emerging but limited scientific evidence supporting its potential usefulness. Preclinical studies, primarily using animal models and in vitro experiments, have demonstrated that resveratrol can modulate several molecular pathways involved in psoriasis pathogenesis, such as the inhibition of NF-κB activation, reduction of pro-inflammatory cytokines (e.g., TNF-α, IL-17, IL-23), and suppression of keratinocyte hyperproliferation.

A few small-scale studies and experimental models suggest that topical or systemic resveratrol may reduce psoriatic lesion severity by attenuating inflammation and oxidative stress. For example, a 2011 study in mice showed that topical resveratrol reduced epidermal thickness and inflammatory cell infiltration. However, clinical evidence in humans is scarce; there are no large, well-controlled clinical trials to conclusively support its efficacy or safety for psoriasis patients. In addition, the bioavailability of resveratrol when taken orally is relatively low, which may limit its therapeutic potential unless formulated for improved delivery.

Overall, while the mechanistic rationale and preclinical findings are promising, the current level of scientific evidence is limited, and further research—including robust human clinical trials—is needed before resveratrol can be considered a validated treatment option for psoriasis.

More about resveratrol
More about Psoriasis

Other ingredients used for Psoriasis

Alfalfa
algal oil
Aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (Vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
Fumaric Acid
Ficus religiosa
Frankincense
Gallic Acid
Glycolic acid
Glucosylceramide
Glycyrrhetinic Acid
Glycyrrhizin
Hyperoside
Hellebore
Henna
isoliquiritigenin
Jojoba Oil
Kaempferol
Lycium
Loquat
Lactobacillus plantarum
Ledebouriella
Linseed Oil
Liverwort
Mucilage
Marine fat
Naringenin
Osthole
Piperine
Polyunsaturated Fat
Polypodium
PhosphatidylGlycerol
Paeoniflorin
Palmitoylethanolamide (PEA)
Rockweed
Sanguisorba
Salmon Oil
Slippery Elm
Semecarpus anacardium
Sulfur
Sargassum
Thuja
Tea Tree Oil
vegetable oil
Verbascoside
Withanolides
walnut
Xanthophyll
Xanthorrhizol
Xanthone

Products containing resveratrol

Vitabase Active Woman's Multi
Thorne Advanced Nutrients Multivitamin
Designs For Health ArthroSoothe™
Designs For Health ArthroSoothe™ Supreme
Pure Encapsulations Balanced Immune
Designs For Health BioFizz® Immune
Designs For Health CellGuard-NR 60 Capsules
Designs For Health FemGuard+Balance™
Designs For Health Inflammatone™
Designs For Health Inflammatone™
Klean Athlete Klean Multivitamin ™
Thorne L-Arginine Plus Perfusia Plus
Pure Encapsulations Memory Pro
Pure Encapsulations Memory Pro
Pure Encapsulations Metabolic Xtra
Douglas Laboratories Methlyated Resveratrol Plus
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Thorne PolyResveratrol-SR
Designs For Health Primal Multi™
Pure Encapsulations Renual
Pure Encapsulations ResCu-SR®
Thorne ResveraCel
Pure Encapsulations Resveratrol
Pure Encapsulations Resveratrol
Douglas Laboratories Resveratrol
Pure Encapsulations Resveratrol Extra
Pure Encapsulations Resveratrol Extra
Designs For Health Resveratrol Supreme
Integrative Therapeutics Resveratrol Ultra HP 175mg
Pure Encapsulations Resveratrol VESIsorb®
Pure Encapsulations RevitalAge™ Ultra
Designs For Health Ultimate Antiox Full Spectrum
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Pure Encapsulations Ultra Pure Pack
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs
Vitabase Women's Support