Relationship: Psoriasis and vitamin A

Evidence supporting the use of: Vitamin A
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin A is scientifically validated for use in the treatment of psoriasis, primarily in the form of its synthetic derivatives known as retinoids. Retinoids, like acitretin and formerly etretinate, are systemic medications derived from vitamin A and are approved for the treatment of moderate to severe psoriasis. Topical retinoids such as tazarotene are also used for milder forms or localized plaques.

The rationale for using vitamin A derivatives in psoriasis centers on their ability to normalize keratinocyte differentiation and proliferation. Psoriasis is characterized by hyperproliferation and abnormal differentiation of skin cells, leading to the formation of thick, scaly plaques. Retinoids modulate gene expression in skin cells, reducing their proliferation and promoting more normal maturation. They also possess anti-inflammatory properties, which can help decrease the inflammation associated with psoriatic lesions.

Multiple randomized controlled trials and clinical guidelines support the efficacy of retinoids in treating psoriasis, particularly when other therapies are ineffective or inappropriate. However, due to potential side effects—including teratogenicity, mucocutaneous symptoms, and liver toxicity—retinoids are generally reserved for carefully selected patients.

In summary, the use of vitamin A derivatives for psoriasis is grounded in robust scientific evidence, with established efficacy and a well-understood mechanism of action, though careful patient selection and monitoring are essential due to the risk of adverse effects.

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Other ingredients used for Psoriasis

alfalfa
algal oil
aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
walnut

Products containing vitamin A

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Evidence supporting the use of: Vitamin A
For the health condition: Psoriasis

Table of Contents

Synopsis

Other ingredients used for Psoriasis

Other health conditions supported by vitamin A

Products containing vitamin A

Health Concerns

Brands

Evidence supporting the use of: Vitamin AFor the health condition: Psoriasis

Table of Contents

Synopsis

Other ingredients used for Psoriasis

Other health conditions supported by vitamin A

Products containing vitamin A

Evidence supporting the use of: Vitamin A
For the health condition: Psoriasis