Evidence supporting the use of: Vitamin E (tocotrienol unspecified)
For the health condition: Psoriasis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin E, including tocotrienols (although most studies focus on tocopherols), has traditionally been used as a complementary approach for skin conditions like psoriasis. The rationale is based on Vitamin E's antioxidant and anti-inflammatory properties, which are thought to help reduce oxidative stress and inflammation in the skin. Historical and anecdotal reports suggest topical or oral use of Vitamin E may improve symptoms such as scaling and erythema. However, scientific studies specifically examining Vitamin E for psoriasis are limited and show mixed results. Some small-scale studies and case reports note mild improvements in skin lesions when topical Vitamin E is used, but larger, well-controlled clinical trials are lacking. The bulk of traditional use is grounded in the general skin-protective reputation of Vitamin E, rather than robust data. Importantly, most studies use tocopherol forms rather than tocotrienols, so evidence for tocotrienols is even more limited. Overall, while Vitamin E is commonly included in traditional and over-the-counter psoriasis remedies, the scientific evidence for significant benefit remains weak, and its use is primarily justified by historical and anecdotal practice rather than rigorous clinical validation.

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