Evidence supporting the use of: Estrogen
For the health condition: Puberty (hormone balancer)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Estrogen is scientifically validated for use in supporting or inducing puberty, particularly in individuals with delayed puberty due to hypogonadism or other conditions affecting endogenous estrogen production. In cisgender girls with primary ovarian insufficiency or Turner syndrome, exogenous estrogen is prescribed to initiate and progress the development of secondary sexual characteristics such as breast development, uterine growth, and the accrual of bone mass. Estrogen therapy is also a cornerstone of gender-affirming hormone therapy for transgender females (male-to-female), where it induces feminizing physical changes consistent with female puberty.

The use of estrogen in these contexts is supported by decades of clinical research and guidelines from major medical organizations, including the Endocrine Society and pediatric endocrine societies. Evidence from randomized controlled trials, observational studies, and long-term cohort studies establishes the efficacy and safety of carefully titrated estrogen therapy for pubertal induction and maintenance. Protocols are well-established, with dosing regimens tailored to mimic natural pubertal progression, minimize risks, and optimize physical and psychosocial outcomes.

In summary, estrogen’s use to support or induce puberty is a scientifically validated medical intervention, with a robust evidence base outlining its benefits and protocols for safe administration.

More about Estrogen
More about Puberty (hormone balancer)

Other ingredients used for Puberty (hormone balancer)

chaste tree
maca
zinc
Estrogen

Products containing Estrogen

We currently have no products on Vitabase that contain this ingredient.