Evidence supporting the use of: Testosterone precursor (unspecified)
For the health condition: Puberty (hormone balancer)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Testosterone precursors, such as androstenedione and dehydroepiandrosterone (DHEA), have scientific validation for use in supporting or treating puberty, particularly in cases where endogenous testosterone production is insufficient (e.g., delayed puberty in males due to hypogonadism). The primary scientific support comes from clinical studies and established endocrinological practice, where exogenous androgens or their precursors are administered to induce and promote the development of secondary sexual characteristics in adolescents with delayed or absent puberty due to hormonal deficiencies. These compounds serve as substrates for enzymatic conversion into testosterone, thereby elevating serum testosterone levels and facilitating normal pubertal progression. While direct use of unspecified "testosterone precursors" is less common than the use of testosterone itself or specific, well-studied precursors like DHEA or androstenedione, the underlying mechanism—supplementing androgenic activity to mimic physiological puberty—is well understood. Medical guidelines recommend careful dosing and monitoring, as inappropriate use can cause adverse effects such as premature epiphyseal closure, mood changes, or virilization. Overall, the evidence base for using testosterone precursors in hormone replacement therapy for pubertal induction is robust, especially when overseen by a specialist. However, the use of "unspecified" testosterone precursors outside of approved pharmaceutical preparations or without medical supervision is not supported.
More about Testosterone precursor (unspecified)
More about Puberty (hormone balancer)
Other health conditions supported by Testosterone precursor (unspecified)
AnemiaAthletic and Exercise Aids
Depression
Muscle Tone (lack of)
Osteoporosis
Puberty (hormone balancer)
Sex Drive (low)
Testosterone (low)