Evidence supporting the use of: Allantoin
For the health condition: Rashes and Hives

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allantoin is a compound commonly found in cosmetic and dermatological products, and its use for rashes and hives is supported by some scientific evidence, though the data are not robust. Allantoin is valued for its keratolytic (exfoliating) and moisturizing properties, as well as its ability to promote skin healing. Several in vitro and in vivo studies demonstrate that allantoin can enhance the proliferation of epithelial cells and support wound healing. Its anti-irritant and soothing effects are also documented, which may help alleviate symptoms associated with minor skin irritations, such as rashes.

However, when it comes specifically to hives (urticaria), which are primarily driven by histamine release and are often allergic in nature, allantoin does not address the underlying immunological mechanisms. Its benefit is limited to providing a soothing effect and supporting skin barrier repair after irritation or scratching.

Overall, while allantoin is scientifically recognized for supporting the healing of minor skin injuries and irritations (including mild rashes), there is a lack of high-quality clinical trials directly evaluating its effectiveness in treating rashes and hives. Its use is thus based on a combination of mechanistic studies, some clinical observations, and its established safety profile in topical formulations.

More about Allantoin
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Products containing Allantoin

We currently have no products on Vitabase that contain this ingredient.