Evidence supporting the use of: Stephania root
For the health condition: Rashes and Hives

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Stephania root, particularly from Stephania tetrandra (also known as Han Fang Ji), has a long history of use in Traditional Chinese Medicine (TCM). In TCM, it is commonly prescribed for edema, rheumatism, and conditions associated with "wind-dampness," which can include some skin manifestations like rashes or hives. The traditional theory posits that Stephania root helps "clear heat" and "expel wind," which are often implicated in eruptions such as urticaria (hives) and other skin rashes. However, the evidence supporting its use for rashes and hives is primarily anecdotal and based on historical practice rather than modern clinical trials.

Scientifically, there is limited research specifically addressing the efficacy of Stephania root for rashes or hives. Most available studies focus on its anti-inflammatory and immunomodulatory properties, which are theoretically relevant, but these have not been robustly tested in the context of skin conditions like hives or allergic rashes. As a result, while traditional use exists, there is minimal modern scientific validation for this specific indication. The overall evidence is weak, and caution must be exercised due to potential toxicity and identification issues (such as confusion with Aristolochia species, which are nephrotoxic). Therefore, the use of Stephania root for rashes and hives is justified by tradition rather than science.

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