Evidence supporting the use of: Terpinen-4-ol
For the health condition: Rashes and Hives

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Terpinen-4-ol is a major component of tea tree oil (Melaleuca alternifolia) and has been studied for its anti-inflammatory and antimicrobial properties. While tea tree oil has a long tradition of use for various skin conditions, including rashes and hives, the scientific evidence specifically for Terpinen-4-ol is limited but growing. Laboratory studies have demonstrated that Terpinen-4-ol can modulate inflammatory responses by inhibiting the production of pro-inflammatory cytokines and mediators such as TNF-α and IL-1β in vitro and in animal models. This suggests a potential mechanism for reducing inflammation associated with skin rashes. Additionally, Terpinen-4-ol exhibits antimicrobial activity against bacteria and fungi commonly involved in skin infections, which may indirectly benefit some types of rashes that have an infectious component.

However, clinical studies directly evaluating Terpinen-4-ol (rather than tea tree oil as a whole) for the treatment of rashes or hives in humans are scarce. Most available evidence comes from broader studies on tea tree oil or from preclinical research. While some small clinical trials and case reports indicate that tea tree oil preparations (containing Terpinen-4-ol) can help with inflammatory skin conditions, high-quality randomized controlled trials are lacking specifically for hives (urticaria) and nonspecific rashes. Thus, the use of Terpinen-4-ol for rashes and hives has some scientific basis, but the overall evidence remains preliminary and not robust enough for strong clinical recommendations.

More about Terpinen-4-ol
More about Rashes and Hives

Other ingredients used for Rashes and Hives

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Akebia
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Alstonia scholaris
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bee propolis
bentonite
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betony
birch
bisabolene
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black poplar
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blue flag
bogbean
borage
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burdock
burning bush
Calotropis gigantea
camphor oil
Campylandra fimbriata
cedar
chamomile
chickweed
chinatree
Chiococca alba
cleavers
Clerodendrum indicum
cocklebur
copaiba oil
coriander
corktree
cowslip
cucumber
Cyathula
David\'s milkberry
dendramine
devil\'s club
divi-divi
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emu oil
Erythropalum scandens
Eupatorium
fang-feng
Ficus religiosa
fireweed
fleabane
four-leaved grass
frankincense
Galbanum
Gardenia jasminoides
Genipa americana
genipap
geranium
golden eye-grass
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gotu kola
Gumweed
Heartsease
heather
Heliopsis
henna
Homalomena
Immortelle
immunoglobin G
Indian nightshade
Indian sarsparilla
Japanese sophora
Jessica\'s sticktight
Jewelweed
jojoba oil
juniper berries
Labdanum
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Large-leaved linden
Ledebouriella
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licorice root
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liverwort
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lovage
Lygodium
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manzanita
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melaleuca alternifolia
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orchid
oriental arborvitae
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Products containing Terpinen-4-ol

We currently have no products on Vitabase that contain this ingredient.