Evidence supporting the use of: Alder Buckthorn
For the body system: Rectum

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Alder Buckthorn (Frangula alnus) has a long history of traditional use as a natural laxative, primarily to support the health and function of the rectum and the broader lower digestive tract. Its bark contains anthraquinone glycosides, which, after being metabolized by gut bacteria, stimulate peristalsis (the muscular contractions of the colon) and increase water content in the stool, thereby easing defecation. This mechanism supports its traditional role in alleviating constipation and promoting bowel movements, effects directly relevant to rectal health.

Historically, the bark was dried and aged (to reduce potential gastrointestinal irritation) and then used in various remedies across Europe. Its use is well-documented in herbal medicine literature from the Middle Ages onward. While the effectiveness of Alder Buckthorn as a laxative is supported by traditional use and some modern herbal pharmacopoeias, rigorous high-quality clinical trials are limited. However, related species such as Rhamnus purshiana (Cascara sagrada) and Rhamnus cathartica have better-established efficacy profiles for similar uses.

Safety concerns exist, including cramping, diarrhea, and potential dependency with long-term use. Regulatory authorities such as the European Medicines Agency acknowledge its traditional use, but recommend it only for short-term relief of occasional constipation. In summary, while there is strong historical and traditional support for Alder Buckthorn’s use to support the rectum (specifically via its laxative action), scientific validation is limited, hence the evidence rating of 3.

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