Evidence supporting the use of: Cascara
For the body system: Rectum

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Cascara (Cascara sagrada, or Rhamnus purshiana) has a long history of traditional use as a natural laxative. Native American peoples and later European settlers used the dried bark of the cascara tree to relieve constipation and promote regular bowel movements. While the term "rectum body system" is not standard in scientific literature, cascara's laxative effect directly impacts the lower gastrointestinal tract, including the rectum, by stimulating bowel movements and facilitating stool passage.

The active compounds in cascara, primarily anthraquinone glycosides (such as cascarosides), increase peristalsis and decrease water absorption in the colon, leading to softer stools. The FDA previously approved cascara as an over-the-counter laxative, but concerns about safety and lack of modern clinical trials led to its removal from the list of generally recognized as safe and effective (GRASE) ingredients in 2002. However, its traditional use for occasional constipation and rectal evacuation is well-documented in herbal medicine texts and historical records.

In summary, cascara's support for the "rectum body system" is justified by strong traditional use and some understanding of its mechanism of action, but robust modern clinical evidence is limited. Caution is advised with long-term use due to potential side effects such as electrolyte imbalance and dependency.

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