Evidence supporting the use of: Docusate Sodium
For the body system: Rectum

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Docusate sodium is a well-established stool softener widely used to manage constipation, particularly when straining should be avoided (e.g., after rectal surgery or in patients with hemorrhoids). Its primary mechanism involves reducing the surface tension of the stool, allowing water and fats to penetrate more easily, thereby softening fecal matter and making it easier to pass. The direct benefit to the rectum and lower gastrointestinal tract is the reduced trauma and discomfort during defecation, which is particularly valuable in those with anorectal disorders or following surgical interventions.

Numerous clinical guidelines and studies support the use of docusate sodium for short-term relief of constipation and to prevent straining. For example, the American Society of Colon and Rectal Surgeons includes docusate among recommended agents for managing constipation in patients with anorectal pathology. However, while docusate is effective as a stool softener, systematic reviews (such as those cited by the Cochrane Database) suggest its efficacy is modest compared to other laxatives like polyethylene glycol or stimulant agents. Nonetheless, its gentle action and good safety profile make it a staple in constipation management related to rectal health.

In summary, docusate sodium is scientifically validated for supporting the rectum and lower gastrointestinal tract, primarily by facilitating easier and less traumatic bowel movements in individuals at risk for rectal injury or discomfort.

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Products containing Docusate Sodium

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