Evidence supporting the use of: Hydroxyanthracene derivative
For the body system: Rectum

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Hydroxyanthracene derivatives, such as those found in senna (Senna alexandrina), cascara, and aloe species, have a long history of traditional use as stimulant laxatives for supporting the rectum and overall bowel function. These compounds are primarily used to relieve occasional constipation by promoting bowel movements. Their mechanism involves stimulating peristalsis (the contractions of the colon) and altering fluid secretion in the intestines, which leads to softer and more frequent stools. The use of hydroxyanthracene-containing plants dates back centuries in various traditional medical systems, including Ayurveda and traditional European medicine. While modern clinical evidence is somewhat limited, there are studies supporting their short-term efficacy in relieving constipation, often seen in the context of bowel preparation or occasional short-term use. However, long-term use is discouraged due to potential side effects such as electrolyte imbalance, dependency, and possible damage to the colon lining. Regulatory authorities in Europe have also issued warnings about the chronic use of these products. Overall, the support for the use of hydroxyanthracene derivatives in aiding the rectum and bowel function is primarily rooted in traditional use, with moderate scientific validation for short-term efficacy but significant concerns about safety in prolonged use.

More about Hydroxyanthracene derivative
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Other body systems supported by Hydroxyanthracene derivative

Digestive System
Gastrointestinal Tract
Intestinal System
Large Intestines (Colon)
Rectum

Products containing Hydroxyanthracene derivative

We currently have no products on Vitabase that contain this ingredient.