Evidence supporting the use of: Lactobacillus (unspecified)
For the body system: Rectum

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus is a genus of probiotic bacteria commonly used to support gastrointestinal and rectal health. There is a moderate level of scientific evidence supporting its use for rectal and lower gastrointestinal issues, primarily in the context of managing symptoms related to conditions such as ulcerative colitis, pouchitis, and radiation-induced proctitis. Several randomized controlled trials and meta-analyses have shown that specific strains of Lactobacillus, often in combination with other probiotics, can help reduce inflammation, improve mucosal healing, and decrease the frequency or severity of diarrhea and rectal discomfort in these patient populations.

For example, studies have found that multi-strain probiotic formulations containing Lactobacillus species can assist in maintaining remission in ulcerative colitis and reducing the severity of pouchitis after surgical interventions. Additionally, there is some evidence that topical application (such as probiotic enemas) may benefit patients with distal ulcerative colitis and some forms of proctitis. However, the strength of the evidence varies depending on the specific condition, strain, and formulation, and not all studies have shown positive effects.

Overall, while traditional use specifically for “rectum” health is limited, the scientific literature does provide moderate support for the use of certain Lactobacillus strains in managing lower gastrointestinal tract conditions that affect the rectum. More research is needed to clarify optimal strains, dosages, and patient populations.

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