Evidence supporting the use of: Diindoylmethane
For the body system: Reproductive System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found naturally in cruciferous vegetables like broccoli and Brussels sprouts. Its use for reproductive system support, particularly in relation to hormone balance, is primarily grounded in scientific investigation. Research indicates that DIM can influence estrogen metabolism by promoting the formation of less potent estrogen metabolites, which may help maintain a healthy estrogen balance. This is particularly relevant for conditions influenced by estrogen dominance, such as premenstrual syndrome (PMS), certain types of breast pain, and symptoms associated with menopause. Some studies suggest DIM may modulate androgen and estrogen activity, which has led to interest in its potential role in supporting prostate health in men and alleviating some symptoms of estrogen-related conditions in women. However, while animal and in vitro studies are promising, and some small human studies have demonstrated changes in estrogen metabolite ratios, robust clinical evidence in large, well-controlled human trials is still lacking. Thus, while DIM is scientifically investigated for reproductive system support, especially hormone modulation, the current evidence is moderate and not definitive. It should not replace conventional therapy for hormonal or reproductive system disorders but may be considered as a supplemental approach under professional supervision.
Other ingredients that support Reproductive System
Acetyl L-carnitineamino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
lactobacillus crispatus
lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
marine lipid
melatonin
moringa
motherwort
muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
water
wild yam
zinc
sarsaparilla
red clover
suma
squawvine
mugwort
nut grass
anise
punarnava
smilax
chaff flower
Szechuan lovage
yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
morinda
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
wood betony
hypothalamus
herbal blend (proprietary)
yohimbe
25-d-spirosta-3, 5-diene
5-methyltetrahydrofolate glucosamine
8-Prenylnaringenin
Antler
Arachidonic Acid
Achyranthes
Anamu
Alchemilla
Aletris
Anserina
Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Abuta
Allium tuberosum
Animal protein
Blue Cohosh
Babchi
Baliospermum
Black galingale
Beef
Beef liver
Bugbane
Bulbine natalensis
Black Gram
Banyan
Ba Ji Tian
Barbasco
Bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchicides
Cohosh
Clary sage
Chinese Mountain Ant
Cucurbita
Cod Liver Oil
Codonopsis
Cnidium
Clerodendrum phlomidis
Cynomorium
Cyathula
Chinese Pond Turtle
Chlorophytum
Chuchuhuasi
Casticin
Campylandra fimbriata
Catuaba
Costus
Carthamus
Canscora
DHEA
Daidzein
Deer Velvet
Dong Quai
Dibenzo-alpha pyrones
D-Pinitol
Diosgenin
Date
Eurycomanone
Egg
Euryale seed
Elk antler
Eurycoma Longifolia
Eicosapentaenoic Acid
Embelia
Estrogen
Folic Acid
Flueggea suffruticosa
Fo-Ti
Furostanols
formononetin
Fish
Fatty acids
False Unicorn Root
Fadogia agrestis
Ginsenosides
Guava
Giant Trillium
Horny Goat Weed
Herb Robert
Indian Sarsparilla
Isoflavones
Long Pepper
icariin
Indian Fagonia
Inositol phosphate
Jungli-bean
Jatropha macrantha
Kachnar
Kokilaksha
Lycium
Lilium polyphyllum
Ligustilides
Lodhtree
Lotus
Leptadenia
Laminaria
Lipids
Labisia pumila
Macamides
Maral Root
Mezoneuron benthamianum
Montanoa tomentosa
Matico
Matapalo Tree
Miroestrol
Marine fat
Mandrake
Millettia
Macaenes
Nigella Seed
Ocotillo
Orchis latifolia
Orchid
Osthole
Puerain
Phyllanthus
Puerarin
Piper chaba
Propionyl-L-Carnitine
Polyunsaturated Fat
Protodioscin
Probiotics
Phlomis umbrosa
Paris polyphylla
Pedalium
portulaca
Phytoestrogens
Polygonum
Petiveria
Peptides
Rue
Rubus
Rehmannia
Rhaponticum
Rosa laevigata
Sapogenin
Sichuan Lovage
Soy
Selenomethionine
Salvia
Sensitive Plant
Sanguisorba
Safed musli
Shataverins
Shilajit
Sparganium
Tree of heaven
Trichilia catigua
Tynanthus panurensis
Tribulus Terrestris
Vegetable Protein
Vitexicarpin
Viburnum
Vidanga
Vitex Agnus-Castus
Withanolides
yohimbine
Zedoary
Other body systems supported by Diindoylmethane
EstrogenFemale Reproductive System
Immune System
Male Reproductive System
Prostate
Reproductive System