Evidence supporting the use of: Vitamin E (mixed tocopherols)
For the body system: Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, particularly as mixed tocopherols, has a well-documented and longstanding association with reproductive health, supported by both historical and modern scientific evidence. The vitamin was originally named "tocopherol" from the Greek words "tokos" (childbirth) and "pherein" (to bear), after early studies in the 1920s showed that rats fed a diet deficient in Vitamin E developed infertility. In females, Vitamin E deficiency led to fetal resorption, while in males it caused testicular degeneration and loss of fertility. These foundational animal studies provided a strong basis for Vitamin E's traditional use in supporting the reproductive system.

In humans, the evidence is less definitive but suggests a supportive role. Vitamin E acts as a potent antioxidant, protecting reproductive tissues from oxidative damage, which is implicated in infertility, especially in males. Some clinical studies have shown that Vitamin E supplementation can improve sperm motility and reduce oxidative stress in men with infertility. In women, Vitamin E has been investigated for its potential to improve endometrial response and reduce complications in assisted reproductive technologies, though results are mixed and not universally conclusive. Major health authorities recognize Vitamin E as essential for overall reproductive health, but do not endorse high-dose supplementation except in cases of deficiency.

In summary, while the strongest evidence comes from animal studies and antioxidant theory, there is moderate scientific support for Vitamin E's role in reproductive health, justifying its use in this context, particularly as an adjunct in cases of oxidative stress or deficiency.

More about Vitamin E (mixed tocopherols)
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acetyl l-carnitine
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l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-arginine
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licorice root
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Products containing Vitamin E (mixed tocopherols)

We currently have no products on Vitabase that contain this ingredient.