Evidence supporting the use of: Vitamin E (natural tocopherols)
For the body system: Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, particularly in the form of natural tocopherols, is supported by scientific evidence as beneficial for the reproductive system, although the strength of the evidence is moderate rather than definitive. Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. In the context of the reproductive system, oxidative stress has been implicated in reduced fertility and reproductive disorders in both males and females. Several animal studies and some clinical research have shown that vitamin E supplementation can improve reproductive outcomes. For males, vitamin E has been associated with improved sperm motility, count, and reduced sperm DNA damage. For example, randomized controlled trials in subfertile men have found that vitamin E, alone or in combination with other antioxidants, can improve certain semen parameters and may modestly increase pregnancy rates. In females, vitamin E may play a role in endometrial health and has been evaluated for its potential to improve outcomes in women undergoing assisted reproductive technologies, though results are mixed and often limited by small sample sizes.

Historically, vitamin E was first identified in the 1920s as a dietary factor essential for reproduction in rats, earning it the label “antisterility vitamin.” However, while deficiency is rare in humans, supplementation is sometimes used in fertility clinics, but guidelines do not universally recommend it due to inconsistent results and lack of large, well-controlled trials. In summary, there is moderate scientific and historical evidence for vitamin E’s role in supporting reproductive health, but more robust human data are needed to confirm its efficacy.

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Other ingredients that support Reproductive System

Acetyl L-carnitine
amino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
Lactobacillus crispatus
Lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
Marine lipid
Melatonin
Moringa
Motherwort
Muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
Tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
Water
Wild yam
Zinc
sarsaparilla
red clover
suma
squawvine
Mugwort
nut grass
anise
punarnava
smilax
chaff flower
Szechuan lovage
Yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
Morinda
royal jelly
equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
Wood betony
herbal blend (proprietary)
Yohimbe
25-d-spirosta-3, 5-diene
5-methyltetrahydrofolate glucosamine
8-Prenylnaringenin
antler
arachidonic acid
Achyranthes
anamu
Alchemilla
Aletris
Anserina
Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Abuta
Allium tuberosum
animal protein
blue cohosh
babchi
Baliospermum
black galingale
beef
Beef liver
bugbane
Bulbine natalensis
black gram
banyan
ba ji tian
barbasco
bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchioides
cohosh
Clary sage
Chinese mountain ant
Cucurbita
cod liver oil
Codonopsis
Cnidium
Clerodendrum phlomidis
Cynomorium
Cyathula
Chinese pond turtle
Chlorophytum
chuchuhuasi
casticin
Campylandra fimbriata
catuaba
costus
Carthamus
Canscora
DHEA
daidzein
deer velvet
dong quai
dibenzo-alpha pyrones
D-Pinitol
diosgenin
date
eurycomanone
egg
Euryale seed
elk antler
Eurycoma Longifolia
eicosapentaenoic acid
Embelia
estrogen
folic acid
Flueggea suffruticosa
fo-ti
furostanols
formononetin
fish
fatty acids
false unicorn root
Fadogia agrestis
Ginsenosides
Guava
giant trillium
horny goat weed
Herb Robert
Indian sarsparilla
isoflavones
long pepper
icariin
Indian fagonia
inositol phosphate
jungli-bean
Jatropha macrantha
Kachnar
Kokilaksha
Lycium
Lilium polyphyllum
ligustilides
lodhtree
lotus
Leptadenia
Laminaria
lipids
Labisia pumila
macamides
maral root
Mezoneuron benthamianum
Montanoa tomentosa
Matico
Matapalo Tree
Miroestrol
Marine fat
mandrake
Millettia
macaenes
Nigella seed
Ocotillo
Orchis latifolia
orchid
Osthole
Puerain
Phyllanthus
Puerarin
Piper chaba
Propionyl-L-Carnitine
polyunsaturated fat
Protodioscin
probiotics
Phlomis umbrosa
Paris polyphylla
Pedalium
Portulaca
Phytoestrogens
Polygonum
Petiveria
Peptides
rue
Rubus
Rehmannia
Rhaponticum
Rosa laevigata
Sapogenin
Sichuan Lovage
Soy
Selenomethionine
Salvia
Sensitive Plant
Sanguisorba
Safed musli
Shataverins
Shilajit
Sparganium
Tree of heaven
Trichilia catigua
Tynanthus panurensis
Tribulus Terrestris
Vegetable Protein
Vitexicarpin
Viburnum
Vidanga
Vitex Agnus-Castus
Withanolides
Yohimbine
Zedoary

Products containing Vitamin E (natural tocopherols)

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