Evidence supporting the use of: Vitamin E (natural tocopherols)
For the body system: Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, particularly in the form of natural tocopherols, is supported by scientific evidence as beneficial for the reproductive system, although the strength of the evidence is moderate rather than definitive. Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. In the context of the reproductive system, oxidative stress has been implicated in reduced fertility and reproductive disorders in both males and females. Several animal studies and some clinical research have shown that vitamin E supplementation can improve reproductive outcomes. For males, vitamin E has been associated with improved sperm motility, count, and reduced sperm DNA damage. For example, randomized controlled trials in subfertile men have found that vitamin E, alone or in combination with other antioxidants, can improve certain semen parameters and may modestly increase pregnancy rates. In females, vitamin E may play a role in endometrial health and has been evaluated for its potential to improve outcomes in women undergoing assisted reproductive technologies, though results are mixed and often limited by small sample sizes.

Historically, vitamin E was first identified in the 1920s as a dietary factor essential for reproduction in rats, earning it the label “antisterility vitamin.” However, while deficiency is rare in humans, supplementation is sometimes used in fertility clinics, but guidelines do not universally recommend it due to inconsistent results and lack of large, well-controlled trials. In summary, there is moderate scientific and historical evidence for vitamin E’s role in supporting reproductive health, but more robust human data are needed to confirm its efficacy.

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Other ingredients that support Reproductive System

Acetyl L-carnitine
amino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
Lactobacillus crispatus
Lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
Marine lipid
Melatonin
Moringa
Motherwort
Muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
Tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
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Zinc
sarsaparilla
red clover
suma
squawvine
Mugwort
nut grass
anise
punarnava
smilax
chaff flower
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cistanche
dioscorea
dodder
eucommia
ganoderma
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equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
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shepherd's purse
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Aerva lanata
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Agnuside
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Allium tuberosum
animal protein
blue cohosh
babchi
Baliospermum
black galingale
beef
Beef liver
bugbane
Bulbine natalensis
black gram
banyan
ba ji tian
barbasco
bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchioides
cohosh
Clary sage
Chinese mountain ant
Cucurbita
cod liver oil
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costus
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dong quai
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diosgenin
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eurycomanone
egg
Euryale seed
elk antler
Eurycoma Longifolia
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folic acid
Flueggea suffruticosa
fo-ti
furostanols
formononetin
fish
fatty acids
false unicorn root
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giant trillium
horny goat weed
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isoflavones
long pepper
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inositol phosphate
jungli-bean
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ligustilides
lodhtree
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Labisia pumila
macamides
maral root
Mezoneuron benthamianum
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Miroestrol
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mandrake
Millettia
macaenes
Nigella seed
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orchid
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polyunsaturated fat
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rue
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Products containing Vitamin E (natural tocopherols)

We currently have no products on Vitabase that contain this ingredient.