Evidence supporting the use of: Ampelopsin
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ampelopsin, also known as dihydromyricetin, is a flavonoid compound primarily found in Ampelopsis grossedentata. There is some scientific interest in its potential anti-inflammatory and immunomodulatory effects. Preclinical studies, especially those conducted in vitro and in animal models, have suggested that ampelopsin can inhibit the production of pro-inflammatory cytokines, such as TNF-α and IL-1β, and suppress the activation of key signaling pathways implicated in the pathogenesis of rheumatoid arthritis (RA), including NF-κB and MAPK pathways. For example, a 2018 study in the journal International Immunopharmacology reported that ampelopsin attenuated inflammatory responses in collagen-induced arthritis models in mice, reducing joint swelling and histopathological signs of inflammation.

However, while these findings are promising, there is a lack of robust human clinical trials evaluating the efficacy and safety of ampelopsin in RA patients. Most evidence to date is limited to laboratory and animal research, and no major rheumatology guidelines currently recognize ampelopsin as a treatment for RA. Thus, while the use of ampelopsin for rheumatoid arthritis is supported by preliminary scientific studies, the overall quality and quantity of evidence remain low, reflecting a need for further well-designed clinical studies to confirm these effects in humans.

More about Ampelopsin
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fat liver oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin
Gypenoside
Horse Gram
Hyperoside
Hellebore
Hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
Mangiferin
Myricetin
Madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
Proteoglycans
Polydatin
Polyunsaturated Fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing Ampelopsin

We currently have no products on Vitabase that contain this ingredient.