Evidence supporting the use of: Astragalin
For the health condition: Rheumatoid Arthritis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Astragalin is a natural flavonoid compound found in various plants, such as Astragalus membranaceus and Polygonum aviculare. Its use for supporting or treating rheumatoid arthritis (RA) is primarily backed by preclinical (animal and in vitro) scientific studies, rather than traditional medical systems or robust human clinical trials. Several laboratory studies have shown that astragalin has anti-inflammatory and antioxidant properties. For example, research published in International Immunopharmacology (2019) demonstrated that astragalin suppressed inflammatory cytokines and alleviated joint swelling in a mouse model of collagen-induced arthritis, a commonly used animal model for RA. The proposed mechanisms include inhibition of NF-κB and MAPK signaling pathways, which are central to the inflammatory process in RA. However, there are currently no published large-scale human clinical trials evaluating astragalin’s efficacy or safety specifically in RA patients.

Because of this, the evidence supporting the use of astragalin for rheumatoid arthritis is limited to experimental studies in animals and isolated cells, and it has not yet translated into validated clinical recommendations. Therefore, while there is some scientific rationale for its investigation, its use for RA should be considered experimental, and more research—particularly in humans—is needed to determine its effectiveness and safety.

More about Astragalin
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fat liver oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin
Gypenoside
Horse Gram
Hyperoside
Hellebore
Hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
Mangiferin
Myricetin
Madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
Proteoglycans
Polydatin
Polyunsaturated Fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing Astragalin

We currently have no products on Vitabase that contain this ingredient.