Evidence supporting the use of: Borage oil
For the health condition: Rheumatoid Arthritis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Borage oil is derived from the seeds of Borago officinalis and is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid thought to have anti-inflammatory properties. Its use in rheumatoid arthritis (RA) is primarily supported by scientific exploration rather than traditional herbal medicine. Several clinical studies and meta-analyses have examined the effects of GLA supplementation on RA symptoms. For example, randomized controlled trials have shown that GLA from borage oil may lead to modest improvements in joint tenderness, swelling, and morning stiffness in some patients with RA, likely due to GLA’s role as a precursor for anti-inflammatory prostaglandins. However, the evidence is inconsistent: some studies report statistically significant benefits, while others show little or no effect compared to placebo. A 2011 Cochrane review concluded that although GLA-containing oils like borage oil might provide some benefit for RA, the effects are modest and the quality of evidence is low to moderate, largely due to small sample sizes and methodological limitations. Adverse effects are generally mild but can include gastrointestinal upset and, rarely, liver toxicity. In summary, while there is a scientific rationale and some clinical support for borage oil in RA, the evidence is not robust or definitive, and it should not replace conventional therapies. Patients should consult healthcare providers before using borage oil as a supplement.
Other ingredients used for Rheumatoid Arthritis
15,16-Dihydrotanshinone IAbies spectabilis
Abrus
Actaea spicata
adrenal cortex
Akebia
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-lipoic acid
alpha-pinene
alpinia galangal
amber
amentoflavone
AMP-activated protein kinase (AMPK)
ampelopsin
andrographolide
anthocyanidins
anthocyanins
antler
apigenin
apocynin
Aralia
arctiin
arjunic acid
ashwagandha
astaxanthin
astragalin
baicalein
baicalin
barbasco
bee venom
Bergenia
Black Hellebore
Black willow
bogbean
borage oil
Boswellia
Boswellic Acid
bovine cartilage / glycosaminoglycan
C-phycocyanin
cannabidiol
carnosic acid
celery
Cetylated Fatty Acids
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
clematis
Clerodendrum phlomidis
cod liver oil
coenzyme Q10 (CoQ10)
cortisol
curcumin
cyanidin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
Dihomo-gamma-linolenic acid
docosahexaenoic Acid
dong quai root
DPA (docosapentaenoic acid)
eicosapentaenoic acid
Eicosatetraenoic acid
EPA (eicosapentaenoic acid)
evening primrose oil
evening primrose oil
fat liver oil
fisetin
fish protein
flavanols
flavones
Flemingia philippinensis
frankincense
fructoborate
Fumaria parviflora
gamma linolenic acid (GLA)
gamma tocopherol
genistein
Gentiana macrophylla
ginger
ginkgetin
green-lipped mussel
guelder rose
Gypenoside
Harpagoside
Hellebore
horse gram
hydroxytyrosol
Hyperoside
Jatropha macrantha
Kaempferol
krill oil
luteolin
madder
mangiferin
Marine fat
Methylsulfonylmethane (MSM)
Myricetin
Myristoleate
Nobiletin
omega-3 fatty acids
Osthole
Palmitoylethanolamide (PEA)
Phaeophyceae
phospholipids
Piper chaba
Polydatin
polyunsaturated fat
proteoglycans
Puerarin
Qin Jiao
resveratrol
rose hips
Salicin
Salmon Oil
Salvianolic acid
saponins
Schizochytrium
Schizochytrium Oil
Semecarpus anacardium
Shilajit
Silkmoth
Sinomenium acutum
slippery elm bark
smilax
Stearidonic acid
Sulforaphane
sulforaphane glucosinolate
Szechuan lovage
Tanshinone
Taxillus chinensis
teasel
turmeric
Uncaria
Urolithin A
Ursolic Acid
vitamin B6
vitamin C
vitamin D
vitamin D3
Watercress
white willow
Withanolides
Other health conditions supported by borage oil
ArthritisEczema
Inflammation
PMS (general)
Rheumatoid Arthritis
Skin (dry and/or flaky)
Wounds and Sores
Products containing borage oil
Pure Encapsulations
Borage Oil 1,000 mg
Pure Encapsulations
Borage Oil 1,000 mg
Vitabase
Complete Essential Fatty Acids
Pure Encapsulations
EFA Essentials
Douglas Laboratories
Ultra G.L.A. Borage Oil
Douglas Laboratories
Ultra G.L.A. Borage Oil
Pure Encapsulations
VisionPro EPA/DHA/GLA
Pure Encapsulations
VisionPro EPA/DHA/GLA
