Evidence supporting the use of: Clematis
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Clematis has been used in traditional Chinese medicine (TCM) and other herbal systems as a remedy for joint pain and inflammatory conditions, including Rheumatoid Arthritis (RA). In TCM, species such as Clematis chinensis (commonly known as "Wei Ling Xian") are incorporated into formulas intended to dispel "wind-dampness" and alleviate pain, particularly in the context of musculoskeletal disorders like RA. Historical texts describe its use for "bi syndrome," a term encompassing joint pain and stiffness.

Although there is a long-standing tradition of clematis use for arthritis-like symptoms, scientific validation is limited. A few preclinical studies suggest that clematis extracts may have anti-inflammatory effects, potentially by modulating cytokines and reducing swelling in animal models of arthritis. However, rigorous human clinical trials are lacking, and the exact active compounds and mechanisms remain unclear. The available evidence is primarily anecdotal or based on traditional practice, with only preliminary laboratory support.

Therefore, clematis's use in RA is justified mainly by tradition, with weak scientific evidence (level 2 out of 5), and patients should approach its use cautiously. It is always recommended to consult healthcare professionals before using herbal remedies for serious conditions like RA.

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