Evidence supporting the use of: Docosapentaenoic acid
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Docosapentaenoic acid (DPA) is an omega-3 fatty acid found in fish oils and some marine mammal oils. Its use in supporting or treating rheumatoid arthritis (RA) is primarily justified by emerging scientific interest, though the evidence is currently limited and not as robust as that for other omega-3 fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Several studies have demonstrated that the omega-3 family, collectively, has anti-inflammatory properties which may help reduce symptoms of RA such as joint pain and stiffness. However, most clinical trials and meta-analyses have focused on EPA and DHA, with DPA often present in much smaller quantities and less frequently studied in isolation.

Some in vitro and animal studies suggest that DPA can be converted into EPA and DHA in the body and may independently exert anti-inflammatory effects by modulating eicosanoid production and cytokine release. There are also preliminary human studies indicating that higher circulating levels of DPA are associated with lower levels of inflammatory markers. However, there is a lack of large-scale, high-quality randomized controlled trials specifically investigating DPA supplementation for RA. Consequently, while there is a scientific rationale and some supportive data for the anti-inflammatory actions of DPA, the direct evidence for its efficacy in RA is limited, and recommendations for its use are generally extrapolated from broader omega-3 research.

More about Docosapentaenoic acid
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
lingusticum wallichii
amber
teasel
guelder rose
gentiana macrophylla
abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Acetylsalicylic acid
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin
Gypenoside
Horse Gram
Hyperoside
Hellebore
Hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
Madder

Products containing Docosapentaenoic acid

We currently have no products on Vitabase that contain this ingredient.